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Performance Criteria

Sensitivity

Criteria

The sensitivity of the probe is determined directly at the tip of the probe or collimator. In general the necessary sensitivity depends on radionuclide uptake, measurement geometry and time between injection and SLNE. The maximum radionuclide uptake of the sentinel lymph node typically varies between 0.01% and 1% with a median at around 0.1%. The SLNE is mostly performed at the day after 99mTc -Nanocolloid injection. Then about 0.05% to 0.005% of the administered activity can be found in the lymph node intraoperatively. Assuming a typical activity application of 80 MBq a spot of activity between 4 and 40 kBq has to be localized. The sensitivity of the measurement system therefore should be better than 5 cps/kBq.

Crystal Probe's Performance

The Crystal Probe’s sensitivity measures at >10,000 cps/MBq. Optimal results demand a minimum sensitivity of >5,000 cps/MBq. The sensitivity of a probe is very important. The more sensitive the probe, the easier it is to find the sentinel lymph node. Also, a higher sensitive probe will result in injecting less radioactive fluid into the patient. The Crystal Probe is two times more sensitive than required.

Crystal Probe Sensitivity

chart

Measured with a 57Co point source
(150 kBq) >10000 cps/MBq

 


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